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26Oct2025Select date
Check-out
27Oct2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Overview

1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105

Home2 Suites By Hilton Sioux Falls Sanford Medical Center - All-suite hotel with indoor pool near Joe Foss Field Airport

Located in Sioux Falls, this all-suite hotel is connected to Sanford Medical Center via a climate-controlled skywalk. The University of Sioux Falls is a 5-minute walk away, and Augustana College is a half-mile from the property. Amenities include free hot breakfast, an indoor saline swimming pool, a spa tub, and a 24-hour fitness center. The hotel offers a business center, 950 square feet of event space, and free WiFi. Free self-parking is available. The property is pet-friendly and is a 4-minute drive from Denny Sanford Premier Center and 6 minutes from Falls Park.

Additional perks of the hotel

Free grocery delivery to suites

Spin2Cycle combined laundry and fitness facility

Barbecue grills

Full cleaning service every fourth night

Late check-out (where available)

Free parking

Suites and Studios

All accommodations are suites or studios featuring full kitchens with refrigerators, microwaves, dishwashers, stovetops, and kitchenware. Each unit includes a seating area with a work desk, a flat-screen TV, and free WiFi. Accessible rooms with hearing and mobility features are available.

Other conveniences

Ironing facilities

Air conditioning and heating

Tea and coffee maker

Free toiletries and hairdryer

AM/FM alarm clock

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Choose Your Room

Our listed hotels offer a variety of room types—double rooms, family suites, or deluxe options—all with features like breakfast, flexible cancellation policies, and exclusive deals.
King Studio Suite Non-Smoking
2 persons
40 m² 
1 King-size bed
Heating
Air conditioning
Queen Studio Two Queen Beds Non-Smoking
2 persons
40 m² 
2 King Size Beds
Heating
Air conditioning
King Studio Suite Hearing Access or Non-Smoking
2 persons
40 m² 
1 King-size bed
Heating
Air conditioning
Queen Studio Two Queen Beds Mobility Access or Non-Smoking
2 persons
40 m² 
2 King Size Beds
Heating
Air conditioning
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Room Rates & Availability Tracker

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Transportation Tips

Transportation Options

City Centre
Sioux Falls800 m
Airports
Sioux Falls Regional (FSD) 7.9 km
Stronsay (soy) 86.3 km

Amenities

Thoughtful hotel amenities for a comfortable stay

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Luggage storage
  • Lift

Sports & Fitness

  • Fitness centre

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Laundry

Business

  • Business centre
  • Fax/Photocopying

Spa & Leisure

  • Indoor swimming pool
  • Jacuzzi

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Curtains
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Hotel Location

1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
Map view
1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
Nearby
1305 W 18th St In the Sanford USD Medical Center
Sioux Empire Medical Museum
290 m
1001 SW Avenue
Sioux Falls Stadium
530 m
Restaurants
The Co-op of Sioux Falls
860 m
410 W 18th St
Azteca
1.1 km
811 S Minnesota Ave
Toppers Pizza
1.1 km
817 S Minnesota Ave
Taco John's
1.0 km
1100 S Minnesota Ave
Papa John's Pizza
1.1 km
711 S Minnesota Ave
Abelardo's Mexican Food
1.1 km
1200 S Minnesota Ave
Pho Quynh
960 m
1100 W 12th St
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Check-in
26Oct2025Select date
Check-out
27Oct2025Select date
Rooms and Guests2 Guests, 1 Room